Ampure XP Beads

Solid Phase Reversible Immobilization (SPRI)


Please see this CoreGenomics blog for a great explanation about Ampure XP beads!


Here is an example of how the ratio of Ampure XP beads to volume of DNA affects the size outcome. If you were to use 35ul of Ampure Beads to cleanup a PCR reactions that has a volume of 50ul (0.7x ratio), then you could expect all the DNA from 200bp and up to be retained on the beads, and everything below 200bp to be discarded in the washes.


Ratio of AmpureXP : DNA